Pollutants are drivers of
chronic diseases. Biotech can help stop this.

We're turning decades of research into real interventions that protect people from the long-term effect of exposure to pollutants.

Read Our Thesis

Exposure to pollutants contributes to today's chronic disease burden, costing millions of lives and trillions in healthcare spending. How pollutants harm the body has been mapped. The path to therapies has not.

Four rotations to engineer human resilience

1
From
Measuring
Toxicity
To
Target
Discovery
Bench
From: Measuring Toxicity
Classical toxicology generates data for regulators, only cataloging harm.
To: Target Discovery
Harness molecular tox data to discover viable targets and treatments.
2
From
Disease
Treatment
To
Early
Intervention
Translation
From: Disease Treatment
Treatments are used once the disease manifests and much damage is done.
To: Early Intervention
Intervening before disease onset and helping individuals reach their full potential.
3
From
Reactive
Regulations
To
Proactive
Incentives
Policy
From: Reactive Regulations
Environmental policy focuses on cleanup and pollution standards.
To: Proactive Incentives
Create regulatory incentives for interventions that build resilience against pollutants.
4
From
Crisis
Response
To
Engineered
Resilience
Chemical Defense
From: Crisis Response
Defense stockpiles are mostly for acute threats and ignore chronic chemical burdens.
To: Engineered Resilience
Build defense systems that counteract long-term low exposures to pollutants.
Rotation One

At the Lab Bench

From regulatory endpoints to therapeutic targets. We're transforming how toxicology generates actionable molecular insights.

Rotation Two

Translation to the Clinic

Catch cellular damage before disease takes hold. Building the diagnostic and therapeutic pipeline that doesn't exist.

Rotation Three

Policy Reforms

Moving policy beyond damage control. Creating incentives for solutions, not just risk assessment.

Rotation Four

Defense Against Pollutants

Expand chemical defense from acute crises to chronic exposures. Developing biological countermeasures for tomorrow's challenges.

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The Problem is Documented

Decades of epidemiological research have established clear links between exposure to pollutants and chronic disease outcomes.

Exposures Diseases
Air Pollution
Pesticides
PFAS Chemicals
Plasticizers
Heavy Metals
Cancer
Neurological
Cardiovascular
Metabolic
Autoimmune
Neurodevelopmental
Line thickness indicates number of studies. Hover for details.

(full analysis coming soon)

Turning Research into Public Benefit

  • Early interventions stop disease before it starts and save billions in healthcare costs
  • Create a biological paper trail that links harms to the source, holding polluters accountable
Toggle scenarios to explore how savings scale over time Conservative Baseline Optimistic $0 $1T $2T $3T 5yr 10yr 15yr 20yr Avoided Healthcare Costs Research Investment Polluter Liability

(full analysis coming soon)

Government's Legacy Blindspot
Creates a Funding Gap

Only 3% of funding across NIH, EPA, and NSF goes toward understanding the adverse effects of pollutants on human health, despite growing evidence that pollutants play a major role in the rise of chronic illness.

NIH $167B
EPA $98B
NSF $19B
Other Research
Monitoring
Env Health

Source: NIH RePORTER, NSF Award Search, USAspending.gov

(full analysis coming soon)

Join the movement

Whether you're a scientist, funder, or entrepreneur, there's a role for you in building the future of environmental health.

For Funders For Doers