We're Ready to Build
What Should Already Exist

The last century was spent chronicling the harms of environmental exposures on human health.
Now the next decades can be spent engineering ways to curb it.

Environmental exposures contribute to many common health conditions that are on the rise today. Tools that can be harnessed to address the early effects of exposures already exist. A new mental model is needed.

Daniel Goodwin and Sarah Daniels arrived at this problem independently. Daniel came as an entrepreneur, engineer, and field-builder who saw pollution as an untapped molecular challenge for biotech to improve human health. Sarah came as an environmental health scientist frustrated that her field generates new toxicity findings for regulators but lacks data on viable targets for interventions. As co-founder of Homeworld Collective, Daniel hired Sarah in 2024 to lead the Pollution Program, united by a shared conviction: environmental health must stop cataloging harm and start engineering solutions.

We refuse to stop at just measurements

Sarah Daniels, PhD

Sarah is an environmental health scientist whose work sits at the boundary of exposure research and clinical translation. She holds a PhD in Environmental Health Sciences with a focus on blood biomarkers of chemical exposures and disease outcomes. She has spearheaded large population health studies on diabetes, endocrine disruption and gut microbiota dysfunction. Before Homeworld, she co-founded a startup serving communities affected by natural disasters and conducted health services research at the Department of Veterans Affairs. At Homeworld, Sarah has driven the research that has budded into this initiative, through conducting the studies, building the evidence base, and defining the scientific agenda. She now leads Engineered Resilience.

Daniel Goodwin, PhD

Daniel is an entrepreneur, engineer, and field-builder who came to environmental health with a simple premise: pollution is a molecular problem that biotech has yet to take seriously. He holds a PhD from MIT, where he developed advanced tools for neuroscience under Ed Boyden and George Church. He also co-founded MileIQ, which scaled to over a million users before being acquired by Microsoft, bringing a background in computer science, product design, and experimental biology. He co-founded Homeworld Collective to advance biotech solutions at the intersection of human and planetary health. For Engineered Resilience, Daniel has shaped the vision, frameworks, and strategic direction of the initiative.

Building Firsts

At Homeworld, Sarah drove the testing of the thesis. In collaboration with partners, Sarah and team published the first-ever Target Product Profile on a new blood diagnostics for an environmental contaminant. Recognizing an existing demand to measure long-term effects of exposures, she secured the first known funding for blood biomarker discovery linked to past lead (Pb⁺²) exposure.

Daniel and Sarah initiated more action after an infamously severe pollutant exposure. After the largest-ever battery fire was set ablaze in Northern California, they deployed a team to collect environmental and human samples, generating molecular exposure signatures in record time. Their preliminary findings of highly specific immunological responses warrant further analyses and follow-up experiments on these unique samples.

Building on the momentum, Daniel and Sarah co-hosted the first-of-a-kind "Trends to Targets" Workshop. They brought together key stakeholders, healthtech start-up founders, and leading experts in environmental health, policy, and biotech to pressure-test a new framework and chart a research direction focused on identifying addressable targets and developing early interventions to mitigate the effects of harmful environmental exposures.

What Emerged

Incubation at Homeworld provided the activation energy to launch a new initiative dedicated to translating environmental health science into biotech-driven solutions.

Engineered Resilience is what emerged: a platform to drive the field from documenting trends to discovering targets, and to mobilize biotech against the health gap that environmental exposures have created.

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